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4,464 awards
Showing 3151–3200
| Action date | Recipient | Agency | Amount | Description | Sector |
|---|---|---|---|---|---|
| 2026-04-20 | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE | Department of Health and Human Services | $60,700,604 | THE ALZHEIMER'S DISEASE TAU PLATFORM CLINICAL TRIAL - PROJECT SUMMARY / ABSTRACT TAU PROTEIN IS AN ATTRACTIVE AD THERAPEUTIC TARGET BECAUSE THE AMOUNT AND ANATOMICAL DISTRIBUTION OF INSOLUBLE TAU AT AUTOPSY IS STRONGLY CORRELATED WITH THE SYMPTOMS AND SEVERITY OF DISEASE DURING LIFE. MULTIPLE TAU THERAPIES ARE NOW IN CLINICAL TRIALS FOR AD, WITH MANY NEW AGENTS ENTERING THE CLINIC. NEW APPROACHES TO ACCELERATING THEIR CLINICAL DEVELOPMENT ARE URGENTLY NEEDED. A VARIETY OF AD BIOMARKERS NOW EXIST, INCLUDING CSF AND PLASMA BETA AMYLOID RATIOS AND PHOSPHORYLATED TAU (P-TAU) LEVELS, AND AMYLOID AND TAU PET TRACERS, PROVIDING TOOLS TO MEASURE PHARMACODYNAMIC EFFECTS OF AMYLOID AND TAU THERAPIES ON THE CORE BIOLOGY OF AD. THE GOAL OF THE ALZHEIMER’S TAU PLATFORM (ATP) TRIAL IS TO CONDUCT A RANDOMIZED, PLACEBO CONTROLLED, PHASE 2 PLATFORM TRIAL IN PRECLINICAL-PRODROMAL AD THAT WILL SIMULTANEOUSLY TEST AT LEAST TWO DIFFERENT TAU-DIRECTED THERAPIES, ALONE OR IN COMBINATION WITH AN ANTI-AMYLOID THERAPY, TO DETERMINE SAFETY, TOLERABILITY, AND BIOLOGICAL BASED PROOF OF CONCEPT BASED ON THE TAU PET TRACER 18F MK6240 AND OTHER TAU BIOMARKERS. PLATFORM TRIALS CREATE EFFICIENCIES THROUGH GENERATION OF A COMMON CLINICAL TRIAL PROTOCOL AND SHARED PLACEBO GROUPS TO ALLOW A GREATER NUMBER OF THERAPIES TO BE TESTED IN LESS TIME WITH LESS EXPENSE THAN BY CONDUCTING MULTIPLE INDEPENDENT TRIALS. THIS TRIAL WILL TEST 5 THERAPEUTIC HYPOTHESES INVOLVING COMBINATIONS OF 3 DRUGS VERSUS PLACEBO: TWO TAU THERAPIES WILL BE STUDIED IN A 2 X 3 FACTORIAL DESIGN (PLACEBO VS. ANTI-AMYLOID [N=2] X TWO TAU THERAPIES OR PLACEBO [N=3]) FOR 24 MONTHS, IN SIX PARALLEL ARMS. THE KEY INCLUSION CRITERIA FOR ATP WILL BE >20 CENTILOIDS OF AMYLOID PET UPTAKE, 18F MK6240 TEMPORAL ROI SUVR >1.25, WITH A GLOBAL CLINICAL DEMENTIA RATING (CDR) OF 0 OR 0.5 AND MMSE >23. USING THESE CRITERIA, WE ESTIMATE THAT 150 PARTICIPANTS PER ARM WILL BE NECESSARY TO HAVE 80% POWER TO DETECT A 30% SLOWING IN THE ACCUMULATION 18F MK6240 SIGNAL OVER 24 MONTHS OF BLINDED THERAPY. KEY SECONDARY ENDPOINTS WILL BE CHANGES IN PLASMA P-TAU SPECIES (-217, ETC.) AND NEUROFILAMENT LIGHT CHAIN (NFL), CLINICAL RATING SCALES AND VOLUMETRIC MRI. LEVERAGING THE EXPERIENCE AND RESOURCES OF THE NIH AD CLINICAL TRIAL CONSORTIUM (ACTC), WE PROPOSE TO ENROLL 900 PARTICIPANTS AT ~100 ACTC SITES OVER 24 MONTHS, RANDOMIZE THEM 5:1 DRUG:PLACEBO FOR 24 MONTHS OF BLINDED TREATMENT, FOLLOWED BY A 24 MONTH OPEN LABEL EXTENSION. WE AIM TO: 1) TEST THE ABILITY OF TWO TAU-DIRECTED THERAPIES, EITHER ALONE OR IN COMBINATION WITH AN ANTI-AMYLOID THERAPY, TO SLOW THE ACCUMULATION OF TAU PET SIGNAL OVER 24 MONTHS AS COMPARED TO PLACEBO OR ANTI-AMYLOID THERAPY ALONE; 2) TEST THE SAFETY AND TOLERABILITY OF 24 MONTHS OF BLINDED THERAPY FOLLOWED BY AN OPTIONAL 24 MONTH OPEN LABEL EXTENSION OF COMBINATION TAU/ANTI-AMYLOID THERAPY; AND 3) EXPLORE THE ABILITY OF EACH OF TWO TAU DIRECTED THERAPIES TO SLOW DISEASE PROGRESSION AS MEASURED BY CSF AND PLASMA BIOMARKERS (PLASMA P-TAU, NFL), VOLUMETRIC MRI AND CLINICAL ASSESSMENTS (PRECLINICAL ALZHEIMER’S COMPOSITE [PACC], ETC.). IF SUCCESSFUL, THE ATP WILL PROVIDE DATA FOR DECISION-MAKING ABOUT WHICH TAU THERAPIES OR COMBINATIONS TO PURSUE IN LARGER EFFICACY STUDIES, AN ONGOING RESOURCE TO TEST NEW THERAPEUTIC APPROACHES BEYOND TAU, AND WILL IMPROVE UNDERSTANDING OF AD BIOLOGY. | — |
| 2026-04-20 | STATE OF RHODE ISLAND DEPARTMENT OF HEALTH | Department of Health and Human Services | $60,687,199 | RHODE ISLAND IMMUNIZATION AND VACCINES FOR CHILDREN COVID SUPPLEMENTAL | — |
| 2026-04-27 | INTERNATIONAL BUSINESS MACHINES CORPORATION | Department of Veterans Affairs | $60,679,594 | PENSION OPTIMIZATION INITIATIVE TASK ORDER | — |
| 2026-04-06 | LOUISIANA HOUSING CORPORATION | Department of Health and Human Services | $60,669,679 | LIHEAP-2024 | — |
| 2026-04-22 | U.S. COMMITTEE FOR REFUGEES AND IMMIGRANTS, INC. | Department of Health and Human Services | $60,663,512 | RESIDENTIAL (SHELTER AND/OR TRANSITIONAL FOSTER CARE) SERVICES FOR UNACCOMPANIED CHILDREN - LICENSED AND TEXAS-EXEMPT AND FLORIDA-DELICENSED ONLY | — |
| 2026-04-29 | WALSH FEDERAL LLC | Department of Transportation | $60,657,995 | CHS TRACON - CONSTRUCTION | — |
| 2026-03-20 | NEW HAMPSHIRE DEPARTMENT OF HEALTH & HUMAN SERVICES | Department of Health and Human Services | $60,655,445 | STATE OPIOID RESPONSE - THROUGH THE NH STATE OPIOID RESPONSE (SOR) 2024, THE NH DEPARTMENT OF HEALTH AND HUMAN SERVICES WILL INCREASE SERVICES FOR YOUTH AND ADULTS WITH OR AT RISK OF DEVELOPING A SUBSTANCE USE DISORDER (SUD) STATEWIDE. THE CONTINUED FOCUS OF SOR IN NH WILL BE IN ALL REGIONS OF THE STATE, CONTINUING TO CREATE ACCESS TO PREVENTION, HARM REDUCTION, TREATMENT, AND RECOVERY FOR PEOPLE WITH ALL TYPES OF SUBSTANCE USE, SPECIFICALLY FOCUSED ON OPIOID USE DISORDER AND STIMULANT USE DISORDER (O/STIMUD), AS WELL AS ADDRESSING ASSOCIATED CO-MORBIDITIES SUCH AS MENTAL HEALTH, AND PHYSICAL HEALTH, INCLUSIVE OF INFECTIOUS DISEASES. WHILE SERVICES WILL BE MADE AVAILABLE TO ANYONE SEEKING ASSISTANCE IN NH, SPECIAL POPULATIONS WILL REMAIN A PRIORITY. THESE SPECIAL POPULATIONS INCLUDE YOUTH AND YOUNG ADULTS (16-25 YEARS OLD) AND THEIR FAMILIES; OLDER ADULTS; PREGNANT AND PARENTING PEOPLE; INDIVIDUALS WITH OR AT RISK OF HIV/AIDS; THE LGBTQA+ COMMUNITY; CHILDREN, YOUTH AND FAMILIES IMPACTED BY SUD, INCLUDING KINSHIP AND FOSTER CARE FAMILIES; INDIVIDUALS INVOLVED WITH THE JUSTICE SYSTEM; AND THOSE RE-ENTERING THE COMMUNITY POST-INCARCERATION. ADDITIONALLY, NH WILL ADDRESS THE UNIQUE SERVICE NEEDS OF HISTORICALLY UNDERSERVED AND UNDERREPRESENTED POPULATIONS, INCLUDING BUT NOT LIMITED TO RACIAL AND ETHNIC MINORITY GROUPS AND INDIVIDUALS WHO HAVE COMMUNICATION ACCESS NEEDS. IN COORDINATION WITH ALL CURRENT STATE AND FEDERAL FUNDING, SOR INITIATIVES ACROSS NH CONTINUE TO ADDRESS ONGOING CHALLENGES AND COMPLEMENT MULTI-SECTOR EFFORTS ACROSS THE CONTINUUM. NH ANTICIPATES SERVING APPROXIMATELY 6,350 UNDUPLICATED INDIVIDUALS ANNUALLY. NH REQUESTS THE FULL FUNDING AVAILABLE, $29,880,604 ANNUALLY AND INTENDS TO USE THIS GRANT TO SUPPORT ACCESS TO CRITICAL SERVICES THAT ARE NOT ACCESSIBLE FOR POPULATIONS DUE TO INSURANCE COVERAGE BARRIERS, SERVICE CAPACITY GAPS, AND WORKFORCE SHORTAGES. EXAMPLES OF THESE SERVICES INCLUDE MEDICATIONS FOR SUBSTANCE USE DISORDER, PREVENTION MESSAGING, TRAINING, WORKFORCE READINESS OPPORTUNITIES, AND SUPPORT SERVICES THAT INCREASE TREATMENT INITIATION, ENGAGEMENT, AND RETENTION (CHILDCARE, TRANSPORTATION). NH WILL USE THE GOVERNMENT PERFORMANCE AND RESULTS ACT (GPRA) DATA COLLECTION AND NOTICE OF FUNDING OPPORTUNITY (NOFO) FOLLOW-UP REQUIREMENTS TO IDENTIFY THE OUTCOMES OF EACH INITIATIVE FUNDED WITH SOR RESOURCES TO INFORM SUSTAINABILITY PLANS. ALL OF THE PROJECTS PROPOSED MEET THE INTENT OF THE NOFO BY INCREASING ACCESS TO MEDICATIONS FOR SUBSTANCE USE DISORDERS, SUPPORTING THE CONTINUUM OF PREVENTION, HARM REDUCTION, TREATMENT, AND RECOVERY SUPPORT SERVICES FOR OUD AND OTHER CONCURRENT SUBSTANCE USE DISORDERS, AND SUPPORTS THE CONTINUUM OF CARE FOR O/STIMUD INCLUDING THOSE INVOLVING COCAINE AND METHAMPHETAMINE. | — |
| 2026-03-30 | PERATON INC. | Department of Transportation | $60,653,374 | THIS DELIVERY ORDER IS FOR THE RADARS NEEDS PACKAGE. ALL OTHER TERMS AND CONDITIONS OF THE CONTRACT REMAIN UNCHANGED AND IN FULL EFFECT. | — |
| 2026-03-20 | DEPARTMENT OF HUMAN SERVICES COLORADO | Department of Health and Human Services | $60,590,323 | LIHEAP-2022 | — |
| 2026-02-13 | CARAHSOFT TECHNOLOGY CORP | Department of State | $60,572,737 | SPLUNK ELA | — |
| 2026-04-06 | JAEB CENTER FOR HEALTH RESEARCH FOUNDATION, INC. | Department of Health and Human Services | $60,555,044 | PEDIATRIC EYE DISEASE INVESTIGATOR GROUP NETWORK | — |
| 2026-04-29 | EDUCATION & TRAINING RESOURCES LLC | Department of Labor | $60,528,526 | BENJAMIN L. HOOKS JOB CORPS CENTER WITH OUTREACH AND ADMISSIONS&CAREER TRANSITION SERVICES | — |
| 2026-04-17 | RHODE ISLAND DOT | Department of Transportation | $60,496,837 | PROJECT TITLE: DESIGN BUILD SERVICES FOR THE RECONSTRUCTION OF THE I-95 VIADUCT NORTHBOUND, PROVIDENCE - GARVEE FUNDS :::: PROJECT DESCRIPTION: DESIGN BUILD SERVICES FOR THE I-95 VIADUCT NORTHBOUND OVER WOONASQUATUCKET RIVER, AMTRAK NEC, CITY STREETS AND RAMPS, MAJOR REHABILITATION WORK, SUPERSTRUCTURE, AND/OR TOTAL BRIDGE REPLACEMENT. PROVIDENCE - GARVEE FUNDS - PROJECT MANAGER: A. POMPEI | — |
| 2026-04-15 | DOCUMENT STORAGE SYSTEMS, INC. | Department of Veterans Affairs | $60,487,793 | HICBA VIRR SOFTWARE SOLUTION | — |
| 2026-03-20 | PENNSYLVANIA DEPARTMENT OF DRUG AND ALCOHOL PROGRAMS | Department of Health and Human Services | $60,455,223 | SUBSTANCE ABUSE PREVENTION, TREATMENT, AND RECOVERY SERVICES BLOCK GRANT | — |
| 2026-05-12 | PCL CONSTRUCTION INC | Department of State | $60,451,294 | INTERNATIONAL WASTEWATER TREATMENT PLANT REHABILITATION AND EXPANSION PROJECT | — |
| 2026-04-20 | PENNSYLVANIA DEPARTMENT OF MILITARY & VETERANS AFFAIRS | Department of Veterans Affairs | $60,433,857 | VHA CBO PURCHASED CARE | — |
| 2026-02-19 | MLU SERVICES, LLC | Department of Homeland Security | $60,410,205 | LOGISTICS HOUSING OPERATIONS UNIT INSTALLATION, MAINTENANCE AND DEACTIVATION - LOGHOUSE HAULING AND INSTALLING (H&I) AND MAINTENANCE AND DEACTIVATION (M&D) SERVICES UP TO 200 UNITS, CONSTRUCTION IN SUPPORT OF DR-4796-IA IN IOWA | — |
| 2026-03-18 | OS-DB-JV-2 LLC | Department of Veterans Affairs | $60,409,485 | TO PROVIDE JANITORIAL SERVICES AT THE VA CARIBBEAN HEALTHCARE SYSTEM (VACHS), SOUTH BED TOWER (SBT), PONCE OUTPATIENT CLINIC (POPC), AND MAYAGUEZ OUTPATIENT CLINIC (MOPC). | — |
| 2026-05-04 | DEPARTMENT OF HUMAN RESOURCES ALABAMA | Department of Agriculture | $60,394,754 | SNAP STATE ADMINISTRATIVE COSTS | — |
| 2026-05-06 | PERATON INC. | General Services Administration | $60,394,723 | DEFENSE TRAVEL SYSTEM SUSTAINMENT BRIDGE | — |
| 2026-04-22 | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | Department of Health and Human Services | $60,372,420 | ALZHEIMER'S DISEASE GENETICS CONSORTIUM | — |
| 2026-04-30 | GENERAL DYNAMICS INFORMATION TECHNOLOGY, INC. | Department of State | $60,321,779 | 2025 GDIT ENDPOINT | — |
| 2026-04-17 | WVDOT DIVISION OF HIGHWAYS | Department of Transportation | $60,300,000 | PROJECT TITLE: EUGENE A. CARTER MEMORIAL BRIDGE + 3 :::: PROJECT DESCRIPTION: KANAWHA, I 64 - MP 57.448 TO 57.874, JCT I 64 (US 60 - WV 61), BRIDGE REHABILITATION, CONSTRUCTION. | — |
| 2026-04-06 | VALLEY-WIDE HEALTH SYSTEMS | Department of Health and Human Services | $60,277,668 | HEALTH CENTER CLUSTER | — |
| 2026-02-13 | INCENTIVE TECHNOLOGY GROUP LLC | Department of Health and Human Services | $60,266,468 | NCI CBIIT MISSION NEED FOR DIGITAL SUPPORT SERVICES. | — |
| 2026-03-20 | DEPARTMENT OF HUMAN SERVICES COLORADO | Department of Health and Human Services | $60,260,997 | LIHEAP-2021 | — |
| 2026-04-27 | TEXAS DEPARTMENT OF PUBLIC SAFETY | Department of Homeland Security | $60,259,424 | GRANT TO LOCAL GOVERNMENT FOR REPAIR OR REPLACEMENT OF DISASTER DAMAGED FACILITIES | — |
| 2026-04-21 | MANAGEMENT & TRAINING CORPORATION | Department of Labor | $60,255,238 | THIS CONTRACT IS FOR THE OPERATION OF SAN DIEGO JOB CORPS CENTER WITH OUTREACH & ADMISSIONS AND CAREER TRANSITION SERVICES. | — |
| 2026-05-05 | COMMUNITY HEALTH CENTER OF LUBBOCK | Department of Health and Human Services | $60,247,257 | HEALTH CENTER CLUSTER | — |
| 2026-04-06 | SOCIAL SERVICES, VIRGINIA DEPARTMENT OF | Department of Health and Human Services | $60,216,116 | SCSS-2024 | — |
| 2026-03-23 | REPUBLIC OF PALAU | Department of Labor | $60,195,717 | UNEMPLOYMENT INSURANCE | — |
| 2026-04-06 | ILLINOIS DEPARTMENT OF HUMAN SERVICE | Department of Health and Human Services | $60,180,901 | SSBG-2023 | — |
| 2026-05-12 | COGNOSANTE, LLC | General Services Administration | $60,173,772 | THIS CONTRACT IS FOR SERVICES IN SUPPORT OF THE MILITARY ONESOURCE PROGRAM FOR MILITARY MEMBERS AND THEIR FAMILIES, SIMILAR TO A COMMERCIAL EMPLOYEE ASSISTANCE PROGRAM (EAP). | — |
| 2026-04-02 | STATE OF FLORIDA DEPARTMENT OF TRANSPORTATION | Department of Transportation | $60,146,710 | PROJECT TITLE: SR 400 (I-4) E OF SR 522 (OSCEOLA PKWY) TO WEST OF SR 528;ADD LANES & RECONSTRUCT;RIGHT OF WAY;DB :::: PROJECT DESCRIPTION: SR 400 (I-4) E OF SR 522 (OSCEOLA PKWY) TO WEST OF SR 528;ADD LANES & RECONSTRUCT;RIGHT OF WAY;DB | — |
| 2026-04-20 | FLORIDA DEPARTMENT OF VETERANS AFFAIRS | Department of Veterans Affairs | $60,123,157 | VHA CBO PURCHASED CARE | — |
| 2026-03-05 | BAKERRIPLEY | Department of Health and Human Services | $60,106,493 | HEAD START AND EARLY HEAD START | — |
| 2026-05-05 | UNIVERSITY OF OKLAHOMA | Department of Health and Human Services | $60,096,875 | OKLAHOMA SHARED CLINICAL AND TRANSLATIONAL RESOURCES | — |
| 2026-03-17 | ARBOR E & T LLC | Department of Labor | $60,074,989 | OPERATION OF THE PUERTO RICO JOB CORPS CENTERS WITH OUTREACH AND ADMISSIONS AND CAREER TRANSITION SERVICES | — |
| 2026-05-05 | BLUE RIDGE COMMUNITY HEALTH SERVICES, INC. | Department of Health and Human Services | $60,060,471 | HEALTH CENTER CLUSTER | — |
| 2026-04-16 | LOS ANGELES DEPARTMENT OF WATER & POWER | Department of the Interior | $60,000,000 | LOS ANGELES DEPARTMENT OF WATER AND POWER IS PARTNERING WITH LOS ANGELES SANITATION AND ENVIRONMENT TO DESIGN AND CONSTRUCT THE LOS ANGELES GROUNDWATER REPLENISHMENT PROJECT. THE PROJECT WILL PRODUCE PURIFIED RECYCLED WATER BY DIVERTING TERTIARY EFFLUENT FROM THE DONALD C. TILLMAN WATER RECLAMATION PLANT TO A NEW ADVANCED WATER PURIFICATION FACILITY USING MICROFILTRATION, REVERSE OSMOSIS, AND AN ULTRAVIOLET ADVANCED OXIDATION PROCESS. THE PURIFIED WATER WILL THEN BE DELIVERED TO THE HANSEN SPREADING GROUNDS TO REPLENISH THE SAN FERNANDO GROUNDWATER BASIN. THE PROJECT ONCE CONSTRUCTED WILL REDUCE DEPENDENCE ON IMPORTED WATER BY DELIVERING 20,600 ACREFEET PER YEAR OF RECYCLED WATER, ESTABLISHING A NEW LOCAL, AND DROUGHT TOLERANT WATER SUPPLY. FUNDING WILL BE USED TO COMPLETE FINAL DESIGN AND CONSTRUCTION OF IMPROVEMENTS AT THE TERTIARY TREATMENT FACILITY AND THE ADVANCED WATER PURIFICATION FACILITY. | — |
| 2026-04-07 | THE GEO GROUP, INC. | Department of Homeland Security | $59,993,453 | DETENTION, TRANSPORTATION, AND MEDICAL SERVICES FOR DENVER (AURORA) CONTRACT DETENTION FACILITY | — |
| 2026-03-20 | ALLIANCE FOR COMMUNITY EMPOWERMENT, INC. | Department of Health and Human Services | $59,992,040 | HEAD START AND EARLY HEAD START | — |
| 2026-03-20 | PUBLIC HEALTH, CALIFORNIA DEPARTMENT OF | Department of Health and Human Services | $59,970,118 | HIGH-IMPACT PREVENTION AND SURVEILLANCE PROGRAMS FOR HEALTH DEPARTMENTS - THIS APPLICATION IS FOR THE FIVE-YEAR FUNDING OPPORTUNITY ANNOUNCEMENT FOR HEALTH DEPARTMENTS TO IMPLEMENT AN INTEGRATED AND COMPREHENSIVE HIV SURVEILLANCE AND PREVENTION PROGRAM TO PREVENT NEW HIV INFECTIONS AND ACHIEVE VIRAL SUPPRESSION AMONG PERSONS LIVING WITH HIV. THIS PROJECT WILL PROMOTE AND SUPPORT IMPROVING HEALTH OUTCOMES FOR PERSONS LIVING WITH HIV THROUGH ACHIEVING AND SUSTAINING VIRAL SUPPRESSION. ACTIVITIES WILL FOCUS ON REDUCING HEALTH-RELATED DISPARITIES BY USING QUALITY, TIMELY, AND COMPLETE SURVEILLANCE AND PROGRAM DATA TO GUIDE HIV PREVENTION EFFORTS. THESE CORE ACTIVITIES CAN BE CONTAINED WITHIN TWO CATEGORIES: (1) PROGRAM PREVENTION; AND (2) PROGRAM SURVEILLANCE. HIV PREVENTION AND SURVEILLANCE PROGRAMS WILL FOCUS ON THE PREVENTION OF NEW HIV INFECTIONS TO IMPROVE THE HEALTH OF PEOPLE WITH HIV. THIS PROJECT WILL INTEGRATE THE WORK OF THE OFFICE OF AIDS’S (OA) HIV SURVEILLANCE AND PREVENTION EVALUATION AND REPORTING (SPER) BRANCH AND HIV PREVENTION BRANCH TO ADDRESS THE EMERGING SYNDEMIC OF HIV, HCV, AND STIS IN CALIFORNIA, AS OUTLINED IN THE 2022-2026 ENDING THE EPIDEMICS: ADDRESSING HIV, HCV, AND STIS IN THE CALIFORNIA STRATEGIC PLAN. THROUGH THIS PLAN, CALIFORNIA ADDRESSES HIV AS A SYNDEMIC WITH HCV AND OTHER STIS THOUGH A SOCIAL DETERMINANTS OF HEALTH LENS, HIGHLIGHTING: A) RACIAL EQUITY, B) HOUSING, C) ACCESS TO HEALTHCARE, D) MENTAL HEALTH AND SUBSTANCE USE, E) ECONOMIC JUSTICE, AND F) STIGMA. OA WILL IMBED THESE PRACTICES INTO SERVICE DELIVERY TO IMPROVE HEALTH EQUITY EFFORTS IN FUNDED JURISDICTIONS BY COORDINATING THESE APPROACHES TO HIV PREVENTION AND TREATMENT RESULTING IN POSITIVE HEALTH OUTCOMES FOR ALL. THE CALIFORNIA EHE PLAN WILL COORDINATE THE WORK OF SIX PHASE I EHE COUNTIES THROUGH 2029: BUILDING ON AND UPDATING THEIR EXISTING EHE PLANS ANNUALLY. THE SIX PHASE I COUNTIES COMPRISE THE CALIFORNIA CONSORTIUM: ALAMEDA, ORANGE, RIVERSIDE, SACRAMENTO, SAN BERNARDINO, AND SAN DIEGO. THE SIX COUNTIES ARE IN VARIOUS GEOGRAPHIC REGIONS AND HAVE DIFFERING PREVENTION NEEDS FOR THEIR DISTINCT POPULATIONS. THUS, CALIFORNIA WILL MAINTAIN AN EHE COORDINATOR AT THE STATE-LEVEL AS WELL AS IN EACH ONE OF THE SIX CALIFORNIA CONSORTIUM COUNTIES. THE WORK OF OUR EHE PLAN WILL: INCREASED LOCAL AVAILABILITY AND ACCESSIBILITY OF INNOVATIVE HIV TESTING SERVICES RESULTING IN INCREASED HIV SCREENING AND ANNUAL RESCREENING AMONG EHE PRIORITY POPULATIONS; BUILD THE CAPACITY FOR RAPID LINKAGE TO CARE, ART AND PREP IN A STATUS-NEUTRAL FRAMEWORK, TO BETTER SERVE EHE PRIORITY POPULATIONS AT THE INTERSECTION OF MENTAL HEALTH, SUBSTANCE USE AND HOUSING STATUS IN EHE COUNTIES; BUILD THE CAPACITY OF EHE COUNTIES TO USE NOVEL, EVIDENCED BASED APPROACHES TO LINK CLIENTS TO PREP/PEP; ENHANCE DATA TO CARE RESPONSE FOR EHE PRIORITY POPULATIONS; AND ENHANCE COMMUNITY ENGAGEMENT TO RECRUIT NEW VOICES AND NON-TRADITIONAL PARTNERS TO THE HIV/STIC/HCV PLANNING TABLE AND TO CONTINUOUSLY IMPROVE EHE INTERVENTIONS. | — |
| 2026-03-20 | CITY OF NEW YORK | Department of Health and Human Services | $59,969,557 | STRENGTHENING STD PREVENTION AND CONTROL FOR HEALTH DEPARTMENTS (STD PCHD). | — |
| 2026-04-06 | HEALTH SERVICES INC | Department of Health and Human Services | $59,923,758 | HEALTH CENTER CLUSTER | — |
| 2026-04-20 | SYSTALEX CORPORATION | Environmental Protection Agency | $59,917,713 | EPA OW OGWDW DWPD IT SYSTEMS SUPPORT SERVICES (DWPD IT SYSTEMS SUPPORT SERVICES) | — |
| 2026-04-20 | MANTECH ADVANCED SYSTEMS INTERNATIONAL, INC. | Department of the Interior | $59,903,462 | PROGRAM EXECUTIVE OFFICE, DEFENSE HEALTHCARE MANAGEMENT SYSTEMS (PEO DHMS) DEFENSE MEDICAL INFORMATION EXCHANGE (DMIX) INTEROPERABILITY SUPPORT SERVICES (DISS) | — |
| 2026-04-17 | STATE OF FLORIDA DEPARTMENT OF TRANSPORTATION | Department of Transportation | $59,868,857 | PROJECT TITLE: SR 30 (US 98) FROM BAYSHORE ROAD TO PORTSIDE DRIVE;ADD LANES & RECONSTRUCT;PRELIMINARY ENGINEER;DB :::: PROJECT DESCRIPTION: SR 30 (US 98) FROM BAYSHORE ROAD TO PORTSIDE DRIVE;ADD LANES & RECONSTRUCT;PRELIMINARY ENGINEER;DB | — |
| 2026-04-20 | HEALTH SERVICES KENTUCKY CABINET FOR | Department of Health and Human Services | $59,829,474 | RYAN WHITE CARE ACT TITLE II | — |
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